Can someone recommend the best anti-spam approach and email service/software?

I was a user of Mailshell’s paid consumer service, which they are discontinuing at the end of this month. The feature i liked best was the disposable email addresses. Being able to just bounce all email from an address once it had been sold was the most effective to me. I never saw any spam and just turned off addresses once spammers got hold of addresses from sometimes legitimate well meaning companies. I never had to worry about false positives or asking people i wanted to correspond with to register.

Maybe the detection technology has improved over the years?

I am aware of four technologies; filters, blacklists, registrations, and disposable addresses.

Anyone want to recommend a best replacement for me? I’m willing to pay for the service. It has to be stable (no service outages), and professional (no advertising added to the email, etc.
I found this list;

http://email. about. com/cs/dispaddrrevs/tp/disposable. htm

Any comments on these services?